Laura Edith Alché
Epidemic conjunctivitis caused by Adenovirus (ADV) are very contagious and people get infected in places where they are in close contact. Herpes simplex virus type 1 (HSV-1) can cause a very serious eye disease, herpetic stromal keratitis, the first cause of infectious blindness in developed countries.
None of these viral eye infections counts on a prophylactic vaccine or specific and/or effective antivirals. To mitigate both diseases, an interdisciplinary research group of virologists, biochemists and organic chemists designed a family of steroidal molecules with antiviral, anti-inflammatory and anti-angiogenic activity, which inhibit viral replication and limit the inflammatory response in vitro and in vivo. The prototype molecule is Virest.
Laura E. Alché has a degree in Biological Sciences from the Faculty of Exact and Natural Sciences (FCEyN) of the University of Buenos Aires (UBA). In 1989, she obtained the degree of Doctor of Biological Sciences, as a result of the research she carried out on the antigenic variability of the Junin virus, agent of Argentine hemorrhagic fever, in vitro and in vivo. She developed her entire academic career as a teacher and researcher in Microbiology and Virology.